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Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity

BACKGROUND: Recently, there has been a surge of interest in developing compounds selectively targeting mitochondria for the treatment of neoplasms. The critical role of mitochondria in cellular metabolism and respiration supports this therapeutic rationale. Dysfunction in the processes of energy pro...

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Bibliografiska uppgifter
Huvudupphovsmän: Millard, Melissa, Pathania, Divya, Shabaik, Yumna, Taheri, Laleh, Deng, Jinxia, Neamati, Nouri
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949386/
https://ncbi.nlm.nih.gov/pubmed/20957228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013131
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