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Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity
BACKGROUND: Recently, there has been a surge of interest in developing compounds selectively targeting mitochondria for the treatment of neoplasms. The critical role of mitochondria in cellular metabolism and respiration supports this therapeutic rationale. Dysfunction in the processes of energy pro...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949386/ https://ncbi.nlm.nih.gov/pubmed/20957228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013131 |
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