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DNA demethylation and histone H3K9 acetylation determine the active transcription of the NKG2D gene in human CD8(+) T and NK cells

The human activating receptor NKG2D is mainly expressed by NK, NKT, γδ T and CD8(+) T cells and, under certain conditions, by CD4(+) T cells. This receptor recognizes a diverse family of ligands (MICA, MICB and ULBPs 1–6) leading to the activation of effector cells and triggering the lysis of target...

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Bibliografski detalji
Glavni autori: Fernández-Sánchez, Alba, Baragaño Raneros, Aroa, Carvajal Palao, Reyes, Sanz, Ana B., Ortiz, Alberto, Ortega, Francisco, Suárez-Álvarez, Beatriz, López-Larrea, Carlos
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549882/
https://ncbi.nlm.nih.gov/pubmed/23235109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23115
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