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DNA demethylation and histone H3K9 acetylation determine the active transcription of the NKG2D gene in human CD8(+) T and NK cells
The human activating receptor NKG2D is mainly expressed by NK, NKT, γδ T and CD8(+) T cells and, under certain conditions, by CD4(+) T cells. This receptor recognizes a diverse family of ligands (MICA, MICB and ULBPs 1–6) leading to the activation of effector cells and triggering the lysis of target...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549882/ https://ncbi.nlm.nih.gov/pubmed/23235109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23115 |
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