Aberrant Keap1 methylation in breast cancer and association with clinicopathological features

Keap1 (Kelch-like ECH-associated protein 1) is an adaptor protein that mediates the ubiquitination/degradation of genes regulating cell survival and apoptosis under oxidative stress conditions. We determined methylation status of the KEAP1 promoter in 102 primary breast cancers, 14 pre-invasive lesi...

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Detalhes bibliográficos
Main Authors: Barbano, Raffaela, Muscarella, Lucia Anna, Pasculli, Barbara, Valori, Vanna Maria, Fontana, Andrea, Coco, Michelina, la Torre, Annamaria, Balsamo, Teresa, Poeta, Maria Luana, Marangi, Giovanni Francesco, Maiello, Evaristo, Castelvetere, Marina, Pellegrini, Fabio, Murgo, Roberto, Fazio, Vito Michele, Parrella, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549873/
https://ncbi.nlm.nih.gov/pubmed/23249627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23319
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