Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome

In light with the view that KEAP1 loss of function may impact tumor behavior and modify response to chemotherapeutical agents, we sought to determine whether KEAP1 gene is epigenetically regulated in malignant gliomas. We developed a Quantitative Methylation Specific PCR (QMSP) assay to analyze 86 m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Muscarella, Lucia Anna, Barbano, Raffaela, D'Angelo, Vincenzo, Copetti, Massimiliano, Coco, Michelina, Balsamo, Teresa, la Torre, Annamaria, Notarangelo, Angelo, Troiano, Michele, Parisi, Salvatore, Icolaro, Nadia, Catapano, Domenico, Valori, Vanna Maria, Pellegrini, Fabio, Merla, Giuseppe, Carella, Massimo, Fazio, Vito Michele, Parrella, Paola
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2011
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092680/
https://ncbi.nlm.nih.gov/pubmed/21173573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.3.14408
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