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iStable: off-the-shelf predictor integration for predicting protein stability changes

BACKGROUND: Mutation of a single amino acid residue can cause changes in a protein, which could then lead to a loss of protein function. Predicting the protein stability changes can provide several possible candidates for the novel protein designing. Although many prediction tools are available, the...

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Autori principali: Chen, Chi-Wei, Lin, Jerome, Chu, Yen-Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549852/
https://ncbi.nlm.nih.gov/pubmed/23369171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S2-S5
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