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O6-methylguanine-DNA methyltransferase (MGMT) Promoter methylation is a rare event in soft tissue sarcoma

BACKGROUND: Gene silencing of O6-methylguanine–DNA methyltransferase (MGMT) by promoter methylation improves the outcome of glioblastoma patients after combined therapy of alkylating chemotherapeutic agents and radiation. The purpose of this study was to assess the frequency of MGMT promoter methyla...

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Detalhes bibliográficos
Main Authors: Jakob, Jens, Hille, Maren, Sauer, Christian, Ströbel, Philipp, Wenz, Frederik, Hohenberger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549846/
https://ncbi.nlm.nih.gov/pubmed/23110891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-7-180
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