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Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domain

BACKGROUND: Scaffold proteins have an important role in the regulation of signal propagation. These proteins do not possess any enzymatic activity but can contribute to the formation of multiprotein complexes. Although scaffold proteins are present in all cell types, the nervous system contains them...

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Detalhes bibliográficos
Main Authors: Pesti, Szabolcs, Balázs, Annamária, Udupa, Roopesh, Szabó, Beáta, Fekete, Anna, Bőgel, Gábor, Buday, László
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549760/
https://ncbi.nlm.nih.gov/pubmed/23181695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-36
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