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Drugging Topoisomerases: Lessons and Challenges
Topoisomerases are ubiquitous enzymes that control DNA supercoiling and entanglements. They are essential during transcription and replication and topoisomerase inhibitors are among the most effective and most commonly used anticancer and antibacterial drugs. This review consists in two parts. In th...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549721/ https://ncbi.nlm.nih.gov/pubmed/23259582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300648v |
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