Nmp4/CIZ Suppresses the Parathyroid Hormone Anabolic Window by Restricting Mesenchymal Stem Cell and Osteoprogenitor Frequency

Parathyroid hormone (PTH) anabolic osteoporosis therapy is intrinsically limited by unknown mechanisms. We previously showed that disabling the transcription factor Nmp4/CIZ in mice expanded this anabolic window while modestly elevating bone resorption. This enhanced bone formation requires a lag pe...

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Détails bibliographiques
Auteurs principaux: He, Yongzheng, Childress, Paul, Hood, Mark, Alvarez, Marta, Kacena, Melissa A., Hanlon, Michael, McKee, Bryce, Bidwell, Joseph P., Yang, Feng-Chun
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2013
Sujets:
Original Research Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549622/
https://ncbi.nlm.nih.gov/pubmed/22873745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0308
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