Nmp4/CIZ Suppresses the Parathyroid Hormone Anabolic Window by Restricting Mesenchymal Stem Cell and Osteoprogenitor Frequency

Parathyroid hormone (PTH) anabolic osteoporosis therapy is intrinsically limited by unknown mechanisms. We previously showed that disabling the transcription factor Nmp4/CIZ in mice expanded this anabolic window while modestly elevating bone resorption. This enhanced bone formation requires a lag pe...

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Detalhes bibliográficos
Main Authors: He, Yongzheng, Childress, Paul, Hood, Mark, Alvarez, Marta, Kacena, Melissa A., Hanlon, Michael, McKee, Bryce, Bidwell, Joseph P., Yang, Feng-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549622/
https://ncbi.nlm.nih.gov/pubmed/22873745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0308
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