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APG: an Active Protein-Gene Network Model to Quantify Regulatory Signals in Complex Biological Systems

Synergistic interactions among transcription factors (TFs) and their cofactors collectively determine gene expression in complex biological systems. In this work, we develop a novel graphical model, called Active Protein-Gene (APG) network model, to quantify regulatory signals of transcription in co...

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Hlavní autoři: Wang, Jiguang, Sun, Yidan, Zheng, Si, Zhang, Xiang-Sun, Zhou, Huarong, Chen, Luonan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549541/
https://ncbi.nlm.nih.gov/pubmed/23346354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01097
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