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APG: an Active Protein-Gene Network Model to Quantify Regulatory Signals in Complex Biological Systems

Synergistic interactions among transcription factors (TFs) and their cofactors collectively determine gene expression in complex biological systems. In this work, we develop a novel graphical model, called Active Protein-Gene (APG) network model, to quantify regulatory signals of transcription in co...

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Detalhes bibliográficos
Main Authors: Wang, Jiguang, Sun, Yidan, Zheng, Si, Zhang, Xiang-Sun, Zhou, Huarong, Chen, Luonan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549541/
https://ncbi.nlm.nih.gov/pubmed/23346354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01097
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