Structural Basis of the Intracellular Sorting of the SNARE VAMP7 by the AP3 Adaptor Complex

VAMP7 is involved in the fusion of late endocytic compartments with other membranes. One possible mechanism of VAMP7 delivery to these late compartments is via the AP3 trafficking adaptor. We show that the linker of the δ-adaptin subunit of AP3 binds the VAMP7 longin domain and determines the struct...

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Main Authors: Kent, Helen M., Evans, Philip R., Schäfer, Ingmar B., Gray, Sally R., Sanderson, Christopher M., Luzio, J. Paul, Peden, Andrew A., Owen, David J.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549491/
https://ncbi.nlm.nih.gov/pubmed/22521722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.01.018
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