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The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation
SNAREs provide energy and specificity to membrane fusion events. Fusogenic trans-SNARE complexes are assembled from Q-SNAREs embedded in one membrane and an R–SNARE embedded in the other. Regulation of membrane fusion events is crucial for intracellular trafficking. We identify the endosomal protein...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605791/ https://ncbi.nlm.nih.gov/pubmed/23104059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2414 |
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