In silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface

Hepatitis C virus (HCV) entry is dependent on host cell molecules tetraspanin CD81, scavenger receptor BI and tight junction proteins claudin-1 and occludin. We previously reported a role for CD81/claudin-1 receptor complexes in HCV entry; however, the molecular mechanism(s) driving association betw...

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Bibliografiske detaljer
Main Authors: Davis, Christopher, Harris, Helen J, Hu, Ke, Drummer, Heidi E, McKeating, Jane A, Mullins, Jonathan G L, Balfe, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2012
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549482/
https://ncbi.nlm.nih.gov/pubmed/22897233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12008
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