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Efficient Intracellular siRNA Delivery by Ethyleneimine-Modified Amphiphilic Macromolecules
New materials that can bind and deliver oligonucleotides such as short interfering RNA (siRNA) without toxicity are greatly needed to fulfill the promise of therapeutic gene silencing. Amphiphilic macromolecules (AMs) were functionalized with linear ethyleneimines to create cationic AMs capable of c...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549469/ https://ncbi.nlm.nih.gov/pubmed/21793212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201100064 |
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