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Scope and Mechanistic Analysis of the Enantioselective Synthesis of Allenes by Rhodium-Catalyzed Tandem Ylide Formation/[2, 3]-Sigmatropic Rearrangement between Donor/Acceptor Carbenoids and Propargylic Alcohols

Rhodium-catalyzed reactions of tertiary propargylic alcohols with methyl aryl- and styryldiazoacetates result in tandem reactions, consisting of oxonium ylide formation followed by [2, 3]-sigmatropic rearrangement. This process competes favorably with the standard O—H insertion reaction of carbenoid...

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Autors principals: Li, Zhanjie, Boyarskikh, Vyacheslav, Hansen, Jørn H., Autschbach, Jochen, Musaev, Djamaladdin G., Davies, Huw M. L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549399/
https://ncbi.nlm.nih.gov/pubmed/22924394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3061529
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