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Magnesium Induced Nucleophile Activation in the Guanylyltransferase mRNA Capping Enzyme

The messenger RNA guanylyltransferase, or mRNA capping enzyme, co-transcriptionally caps the 5′-end of nascent mRNA with GMP during the second in a set of three enzymatic reactions that result in the formation of an N7-methyl guanosine cap during mRNA maturation. The mRNA capping enzyme is character...

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Autori principali: Swift, Robert V., Ong, Chau D., Amaro, Rommie E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549306/
https://ncbi.nlm.nih.gov/pubmed/23205906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301224b
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