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New Insights into the Regulation of Neutrophil NADPH Oxidase Activity in the Phagosome: A Focus on the Role of Lipid and Ca(2+) Signaling

Significance: Reactive oxygen species, produced by the phagosomal NADPH oxidase of neutrophils, play a significant physiological role during normal defense. Their role is not only to kill invading pathogens, but also to act as modulators of global physiological functions of phagosomes. Given the imp...

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Autors principals: Bréchard, Sabrina, Plançon, Sébastien, Tschirhart, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549206/
https://ncbi.nlm.nih.gov/pubmed/22867131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4773
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