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RAC1(P29S) is a spontaneously activating cancer-associated GTPase
RAC1 is a small, Ras-related GTPase that was recently reported to harbor a recurrent UV-induced signature mutation in melanoma, resulting in substitution of P29 to serine (RAC1(P29S)), ranking this the third most frequently occurring gain-of-function mutation in melanoma. Although the Ras family GTP...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549122/ https://ncbi.nlm.nih.gov/pubmed/23284172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220895110 |
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