Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity

Polarization of mammalian neurons with a specified axon requires precise regulation of microtubule and actin dynamics in the developing neurites. Here we show that mammalian partition defective 3 (mPar3), a key component of the Par polarity complex that regulates the polarization of many cell types...

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Autori principali: Chen, She, Chen, Jia, Shi, Hang, Wei, Michelle, Castaneda-Castellanos, David R., Bultje, Ronald S., Pei, Xin, Kriegstein, Arnold R., Zhang, Mingjie, Shi, Song-Hai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549028/
https://ncbi.nlm.nih.gov/pubmed/23273878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.11.014
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