Hyperpolarized (13)C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas

Renal cell carcinomas (RCCs) are a heterogeneous group of tumors with a wide range of aggressiveness. Noninvasive methods to confidently predict the tumor biological behavior and select appropriate treatment are lacking. Here, we investigate the dynamic metabolic flux in living RCC cells using hyper...

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Autori principali: Keshari, Kayvan R., Sriram, Renuka, Koelsch, Bertram L., Van Criekinge, Mark, Wilson, David M., Kurhanewicz, John, Wang, Zhen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548990/
https://ncbi.nlm.nih.gov/pubmed/23204238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3461
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