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Hyperpolarized (13)C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas

Renal cell carcinomas (RCCs) are a heterogeneous group of tumors with a wide range of aggressiveness. Noninvasive methods to confidently predict the tumor biological behavior and select appropriate treatment are lacking. Here, we investigate the dynamic metabolic flux in living RCC cells using hyper...

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Detalles Bibliográficos
Main Authors: Keshari, Kayvan R., Sriram, Renuka, Koelsch, Bertram L., Van Criekinge, Mark, Wilson, David M., Kurhanewicz, John, Wang, Zhen J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548990/
https://ncbi.nlm.nih.gov/pubmed/23204238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3461
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