Загрузка...
Insights into the Role of Heme in the Mechanism of Action of Antimalarials
Using cell fractionation and measurement of Fe(III)heme-pyridine, the antimalarial chloroquine (CQ) has been shown to cause a dose-dependent decrease in hemozoin and concomitant increase in toxic “free” heme in cultured Plasmodium falciparum that is directly correlated with parasite survival. Transm...
Сохранить в:
| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548943/ https://ncbi.nlm.nih.gov/pubmed/23043646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300454t |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|