CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma

CXCR2 in non-small cell lung cancer (NSCLC) has been studied mainly in stromal cells and is known to increase tumor inflammation and angiogenesis. Here, we examined the prognostic importance of CXCR2 in NSCLC and the role of CXCR2 and its ligands in lung cancer cells. The effect of CXCR2 expression...

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Bibliografiske detaljer
Main Authors: Saintigny, Pierre, Massarelli, Erminia, Lin, Steven, Chen, Yulong, Goswami, Sangeeta, Erez, Baruch, O’Reilly, Michael S., Liu, Diane, Lee, J. Jack, Zhang, Li, Ping, Yuan, Behrens, Carmen, Soto, Luisa M. Solis, Heymach, John V., Kim, Edward S., Herbst, Roy S., Lippman, Scott M., Wistuba, Ignacio I., Hong, Waun Ki, Kurie, Jonathan M., Koo, Ja Seok
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548940/
https://ncbi.nlm.nih.gov/pubmed/23204236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0263
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