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Positive feedback produces broad distributions in maximum activation attained within a narrow time window in stochastic biochemical reactions
How do single cell fate decisions induced by activation of key signaling proteins above threshold concentrations within a time interval are affected by stochastic fluctuations in biochemical reactions? We address this question using minimal models of stochastic chemical reactions commonly found in c...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Institute of Physics
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548829/ https://ncbi.nlm.nih.gov/pubmed/23298061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4772583 |
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