Morphine Induces Bacterial Translocation in Mice by Compromising Intestinal Barrier Function in a TLR-Dependent Manner

Opiates are among the most prescribed drugs for pain management. However, morphine use or abuse results in significant gut bacterial translocation and predisposes patients to serious infections with gut origin. The mechanism underlying this defect is still unknown. In this report, we investigated th...

Full description

Saved in:

Bibliographic Details
Main Authors:	Meng, Jingjing, Yu, Haidong, Ma, Jing, Wang, Jinghua, Banerjee, Santanu, Charboneau, Rick, Barke, Roderick A., Roy, Sabita
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2013
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3548814/ https://ncbi.nlm.nih.gov/pubmed/23349783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054040
Tags:	Add Tag No Tags, Be the first to tag this record!

Morphine Induces Bacterial Translocation in Mice by Compromising Intestinal Barrier Function in a TLR-Dependent Manner

Similar Items