Morphine Induces Bacterial Translocation in Mice by Compromising Intestinal Barrier Function in a TLR-Dependent Manner

Opiates are among the most prescribed drugs for pain management. However, morphine use or abuse results in significant gut bacterial translocation and predisposes patients to serious infections with gut origin. The mechanism underlying this defect is still unknown. In this report, we investigated th...

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Autors principals: Meng, Jingjing, Yu, Haidong, Ma, Jing, Wang, Jinghua, Banerjee, Santanu, Charboneau, Rick, Barke, Roderick A., Roy, Sabita
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548814/
https://ncbi.nlm.nih.gov/pubmed/23349783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054040
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