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Mutations in the Hedgehog Pathway Genes SMO and PTCH1 in Human Gastric Tumors

The causal role of the hedgehog pathway in cancer has been best documented in basal cell carcinoma of the skin. To assess potential DNA alterations of the hedgehog pathway in gastric cancer, we sequenced SMO and PTCH1 genes in a set of 39 gastric tumors. Tumors were classified by histology based on...

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Detalhes bibliográficos
Main Authors: Wang, Xi-De, Inzunza, Hector, Chang, Han, Qi, Zhenhao, Hu, Beihong, Malone, Daniel, Cogswell, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548780/
https://ncbi.nlm.nih.gov/pubmed/23349881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054415
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