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A possible involvement of Nrf2-mediated heme oxygenase-1 up-regulation in protective effect of the proton pump inhibitor pantoprazole against indomethacin-induced gastric damage in rats

BACKGROUND: Proton pump is an integral membrane protein that is ubiquitous ATP binding cassette (ABC) involved in many transport processes in all living organisms, among which a specialized form of pump, so called p-type proton pump, exists in the parietal cells of stomach. Though proton pump inhibi...

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Hlavní autoři: Lee, Ho-Jae, Han, Young-Min, Kim, Eun-Hee, Kim, Yoon-Jae, Hahm, Ki-Baik
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548718/
https://ncbi.nlm.nih.gov/pubmed/23066659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-143
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