Deficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mouse

BACKGROUND: The CCAAT/enhancer binding proteins (C/EBPs) play important roles in carcinogenesis of many tumors including the lung. Since multiple C/EBPs are expressed in lung, the combinatorial expression of these C/EBPs on lung carcinogenesis is not known. METHODS: A transgenic mouse line expressin...

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Hlavní autoři: Kimura, Shioko, Paiz, Jorge, Yoneda, Mitsuhiro, Kido, Taketomo, Vinson, Charles, Ward, Jerrold M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548712/
https://ncbi.nlm.nih.gov/pubmed/23234329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-90
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