Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice

NKX2-1 is a homeodomain transcription factor that is critical for genesis of the thyroid and transcription of the thyroid-specific genes. Nkx2-1-thyroid-conditional hypomorphic mice were previously developed in which Nkx2-1 gene expression is lost in 50% of the thyroid cells. Using this mouse line a...

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Detaylı Bibliyografya
Asıl Yazarlar: Hoshi, Sayuri, Hoshi, Nobuo, Okamoto, Minoru, Paiz, Jorge, Kusakabe, Takashi, Ward, Jerrold M., Kimura, Shioko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Carcinogenesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736302/
https://ncbi.nlm.nih.gov/pubmed/19581346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp167
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