Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets

BACKGROUND: Gliomas exhibit high glycolytic rates, and monocarboxylate transporters (MCTs) play a major role in the maintenance of the glycolytic metabolism through the proton-linked transmembrane transport of lactate. However, their role in gliomas is poorly studied. Thus, we aimed to characterize...

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Detalhes bibliográficos
Main Authors: Miranda-Gonçalves, Vera, Honavar, Mrinalini, Pinheiro, Céline, Martinho, Olga, Pires, Manuel M., Pinheiro, Célia, Cordeiro, Michelle, Bebiano, Gil, Costa, Paulo, Palmeirim, Isabel, Reis, Rui M., Baltazar, Fátima
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548586/
https://ncbi.nlm.nih.gov/pubmed/23258846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos298
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