Transcriptional Regulatory Factor X6 (Rfx6) Increases Gastric Inhibitory Polypeptide (GIP) Expression in Enteroendocrine K-cells and Is Involved in GIP Hypersecretion in High Fat Diet-induced Obesity

Gastric inhibitory polypeptide (GIP) is an incretin released from enteroendocrine K-cells in response to nutrient ingestion. GIP potentiates glucose-stimulated insulin secretion and induces energy accumulation into adipose tissue, resulting in obesity. Plasma GIP levels are reported to be increased...

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Autori principali: Suzuki, Kazuyo, Harada, Norio, Yamane, Shunsuke, Nakamura, Yasuhiko, Sasaki, Kazuki, Nasteska, Daniela, Joo, Erina, Shibue, Kimitaka, Harada, Takanari, Hamasaki, Akihiro, Toyoda, Kentaro, Nagashima, Kazuaki, Inagaki, Nobuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548501/
https://ncbi.nlm.nih.gov/pubmed/23192339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.423137
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