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Using Hydrogen/Deuterium Exchange Mass Spectrometry to Define the Specific Interactions of the Phospholipase A(2) Superfamily with Lipid Substrates, Inhibitors, and Membranes

The phospholipase A(2) (PLA(2)) superfamily consists of 16 groups and many subgroups and constitutes a diverse set of enzymes that have a common catalytic activity due to convergent evolution. However, different PLA(2) types have unique three-dimensional structures and catalytic residues as well as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cao, Jian, Burke, John E., Dennis, Edward A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548490/
https://ncbi.nlm.nih.gov/pubmed/23209293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.421909
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