Protein-disulfide Isomerase Regulates the Thyroid Hormone Receptor-mediated Gene Expression via Redox Factor-1 through Thiol Reduction-Oxidation

Protein-disulfide isomerase (PDI) is a dithiol/disulfide oxidoreductase that regulates the redox state of proteins. We previously found that overexpression of PDI in rat pituitary tumor (GH3) cells suppresses 3,3′,5-triiodothyronine (T(3))-stimulated growth hormone (GH) expression, suggesting the co...

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Bibliographic Details
Main Authors: Hashimoto, Shoko, Imaoka, Susumu
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548481/
https://ncbi.nlm.nih.gov/pubmed/23148211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365239
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