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Functional Mapping of the Lectin Activity Site on the β-Prism Domain of Vibrio cholerae Cytolysin: IMPLICATIONS FOR THE MEMBRANE PORE-FORMATION MECHANISM OF THE TOXIN
Vibrio cholerae cytolysin (VCC) is a prominent member in the family of β-barrel pore-forming toxins. It induces lysis of target eukaryotic cells by forming transmembrane oligomeric β-barrel channels. VCC also exhibits prominent lectin-like activity in interacting with β1-galactosyl-terminated glycoc...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548476/ https://ncbi.nlm.nih.gov/pubmed/23209283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430181 |
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