Characterization of Plasmodium falciparum Calcium-dependent Protein Kinase 1 (PfCDPK1) and Its Role in Microneme Secretion during Erythrocyte Invasion

Calcium-dependent protein kinases (CDPKs) play important roles in the life cycle of Plasmodium falciparum and other apicomplexan parasites. CDPKs commonly have an N-terminal kinase domain (KD) and a C-terminal calmodulin-like domain (CamLD) with calcium-binding EF hands. The KD and CamLD are separat...

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Autors principals: Bansal, Abhisheka, Singh, Shailja, More, Kunal R., Hans, Dhiraj, Nangalia, Kuldeep, Yogavel, Manickam, Sharma, Amit, Chitnis, Chetan E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548469/
https://ncbi.nlm.nih.gov/pubmed/23204525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.411934
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