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Design, synthesis and X-ray analysis of a glycoconjugate bound to Mycobacterium tuberculosis Antigen 85C

Tuberculosis (TB) is a global health threat with nearly 500,000 new cases of multidrug-resistance TB estimated to occur every year, so new drugs are desperately needed. A number of current antimycobacterial drugs work by interfering with the biosynthesis of key components of the mycolylarabinogalact...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ibrahim, Diaa A., Boucau, Julie, Lajiness, Daniel, Veleti, Sri Kumar, Trabbic, Kevin R., Adams, Samuel S., Ronning, Donald R., Sucheck, Steven J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548330/
https://ncbi.nlm.nih.gov/pubmed/23190459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc3004342
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