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Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma

Natural killer T (iNKT) cells can help mediate immune surveillance against tumors in mice. Prior studies targeting human iNKT cells were limited to therapy of advanced cancer and led to only modest activation of innate immunity. Clinical myeloma is preceded by an asymptomatic precursor phase. Lenali...

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Detalhes bibliográficos
Main Authors: Richter, Joshua, Neparidze, Natalia, Zhang, Lin, Nair, Shiny, Monesmith, Tamara, Sundaram, Ranjini, Miesowicz, Fred, Dhodapkar, Kavita M., Dhodapkar, Madhav V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548165/
https://ncbi.nlm.nih.gov/pubmed/23100308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-435503
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