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Posttranslational modifications of cardiac ryanodine receptors: Ca(2+) signaling and EC-coupling

In cardiac muscle, a number of posttranslational protein modifications can alter the function of the Ca(2+) release channel of the sarcoplasmic reticulum (SR), also known as the ryanodine receptor (RyR). During every heartbeat RyRs are activated by the Ca(2+)-induced Ca(2+) release mechanism and con...

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Detalhes bibliográficos
Main Authors: Niggli, Ernst, Ullrich, Nina D., Gutierrez, D., Kyrychenko, Sergii, Poláková, Eva, Shirokova, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548064/
https://ncbi.nlm.nih.gov/pubmed/22960642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.08.016
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