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Therapeutic effect of CTLA4-Ig on a murine model of primary biliary cirrhosis
Collectively, the data in both humans and murine models of human primary biliary cirrhosis (PBC) suggest that activated T cells, particularly CD8 T cells, play a critical role in biliary cell destruction. Under physiological conditions, T cell activation involves two critical signals that involve th...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3548049/ https://ncbi.nlm.nih.gov/pubmed/22996325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26067 |
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