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The efficacy and safety of a nicotine conjugate vaccine (NicVAX(®)) or placebo co-administered with varenicline (Champix(®)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

BACKGROUND: A potential new treatment in smoking cessation and relapse prevention is nicotine vaccination which is based on active immunization against the nicotine molecule. This immunization will elicit the immune system to produce nicotine-specific antibodies that sequester nicotine in the blood...

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Bibliografiska uppgifter
Huvudupphovsmän: Hoogsteder, Philippe HJ, Kotz, Daniel, van Spiegel, Paul I, Viechtbauer, Wolfgang, Brauer, Ruth, Kessler, Paul D, Kalnik, Matthew W, Fahim, Raafat EF, van Schayck, Onno CP
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547752/
https://ncbi.nlm.nih.gov/pubmed/23216646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2458-12-1052
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