The efficacy and safety of a nicotine conjugate vaccine (NicVAX(®)) or placebo co-administered with varenicline (Champix(®)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

BACKGROUND: A potential new treatment in smoking cessation and relapse prevention is nicotine vaccination which is based on active immunization against the nicotine molecule. This immunization will elicit the immune system to produce nicotine-specific antibodies that sequester nicotine in the blood...

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Detalhes bibliográficos
Main Authors: Hoogsteder, Philippe HJ, Kotz, Daniel, van Spiegel, Paul I, Viechtbauer, Wolfgang, Brauer, Ruth, Kessler, Paul D, Kalnik, Matthew W, Fahim, Raafat EF, van Schayck, Onno CP
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547752/
https://ncbi.nlm.nih.gov/pubmed/23216646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2458-12-1052
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