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Accurate Sampling of High-Frequency Motions in Proteins by Steady-State (15)N-{(1)H} Nuclear Overhauser Effect Measurements in the Presence of Cross-Correlated Relaxation

The steady-state {(1)H}-(15)N NOE experiment is used in most common NMR analyses of backbone dynamics to accurately ascertain the effects of the fast dynamic modes. We demonstrate here that, in its most common implementation, this experiment generates an incorrect steady state in the presence of CSA...

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Detaylı Bibliyografya
Asıl Yazarlar: Ferrage, Fabien, Cowburn, David, Ghose, Ranajeet
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547682/
https://ncbi.nlm.nih.gov/pubmed/19358609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja809526q
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