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Detection of in vivo Matrix Metalloproteinase Activity using Microdialysis Sampling and Liquid Chromatography-Mass Spectrometry
Matrix metalloproteinases (MMPs) are a family of endoproteases that break down extracellular matrix and whose upregulation contributes to several diseases. An LC/MS/MS method was developed to quantify MMP-1 and -9 substrates and their N-terminal peptide products in samples obtained from implanted mi...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3547635/ https://ncbi.nlm.nih.gov/pubmed/19904964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901703g |
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