Detection of in vivo Matrix Metalloproteinase Activity using Microdialysis Sampling and Liquid Chromatography-Mass Spectrometry

Matrix metalloproteinases (MMPs) are a family of endoproteases that break down extracellular matrix and whose upregulation contributes to several diseases. An LC/MS/MS method was developed to quantify MMP-1 and -9 substrates and their N-terminal peptide products in samples obtained from implanted mi...

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Bibliografiske detaljer
Main Authors: Wang, Ying, Zagorevski, Dmitri V., Lennartz, Michelle R., Loegering, Daniel J., Stenken, Julie A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547635/
https://ncbi.nlm.nih.gov/pubmed/19904964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901703g
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