Nonmuscle Myosin IIB Links Cytoskeleton to IRE1α Signaling during ER Stress

Here we identify and characterize a cytoskeletal myosin protein required for IRE1α oligomerization, activation, and signaling. Proteomic screening identified nonmuscle myosin heavy chain IIB (NMHCIIB), a subunit of nonmuscle myosin IIB (NMIIB), as an ER stress-dependent interacting protein specific...

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Main Authors: He, Yin, Beatty, Alexander, Han, Xuemei, Ji, Yewei, Ma, Xuefei, Adelstein, Robert S., Yates, John R., Kemphues, Kenneth, Qi, Ling
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547290/
https://ncbi.nlm.nih.gov/pubmed/23237951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.11.006
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