Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility

Nonmuscle myosin II (NMII) is uniquely responsible for cell contractility and thus defines multiple aspects of cell behavior. To generate contraction, NMII molecules polymerize into bipolar minifilaments. Different NMII paralogs are often coexpressed in cells and can copolymerize, suggesting that th...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Shutova, Maria S., Asokan, Sreeja B., Talwar, Shefali, Assoian, Richard K., Bear, James E., Svitkina, Tatyana M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584186/
https://ncbi.nlm.nih.gov/pubmed/28701425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705167
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