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Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility

Nonmuscle myosin II (NMII) is uniquely responsible for cell contractility and thus defines multiple aspects of cell behavior. To generate contraction, NMII molecules polymerize into bipolar minifilaments. Different NMII paralogs are often coexpressed in cells and can copolymerize, suggesting that th...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Shutova, Maria S., Asokan, Sreeja B., Talwar, Shefali, Assoian, Richard K., Bear, James E., Svitkina, Tatyana M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584186/
https://ncbi.nlm.nih.gov/pubmed/28701425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705167
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